LGD-4033, also known as Ligandrol or Anabolicum, is a medication used for fixing worn-out muscles caused by neuromuscular diseases or dystrophy. It functions by increasing muscle mass. It is from the household of selective androgen receptor modulators. Here we will review the effects of this drug on the cardiovascular system, bone health, and muscle density.

WHY LGD-4033?

In muscle wasting disorders (MWD) the muscle is diminished and also very feeble which would eventually influence the cardiovascular system and bone health. The heart and bones have major roles to perform in MWD as coronary disorders and osteoporosis influence muscle density.

Why LGD-4033? Ligandrol binds with the androgen receptor located in the body. Androgens are observed predominantly in males and rarely in females.

LGD-4033 can help to increase lean muscle mass in muscle wasting diseases. Aging is a natural process, as we age the integrity of these muscles is lost as the muscle becomes weak and lean. Ligandrol usage can restore muscle power.

Below are the uses of Ligandrol.


Muscle Density

Aging can cause a drop in muscle density and muscle mass. In a clinical study carried out on 30 old people, 15 males and 15 females in precisely the identical community. 15 have been provided a 3-mg loading dosage of LGD-4033 for a span of eight weeks while the other 15 were given a lesser dosage of LGD-4033 to the identical period of time. It was found that the group given a greater dosage had significant changes like improved muscular strength, enhanced physical strength, and better cardiovascular outputs. Meanwhile, another set had little or no substantial alterations.

Ligandrol is used in the management of neuromuscular diseases, geriatrics, and carcinoma patients.

Clinical research or study patterning muscle loss or dystrophy in cancer is still in view.

Cardiovascular Health

The cardiac cycle is one of the most complex cycles of the human body. The center is an extremely muscular organ with a decorative structure. LGD-4033 is essential to individuals who frequently suffer from muscle building and weight loss as a result of cardiac diseases.

In a clinical study that involved 10 patients suffering from cardiac distress. They took a loading dosage of Ligandrol (3mg) for 3 weeks and later reduced to a maintenance dose (1mg) for five weeks. This resulted in huge progress in cardiac readings as there was a drop in cholesterol. The association between the lipid profile along with also the heart muscles is cholesterol when the lipids levels are healthy it prevents cardiovascular heart disease (CHD).

Bone Health

The bone is the frame where the muscles are constructed. Whenever there is a problem with the bone such as osteoporosis that the muscles are weak and can’t build around the bone.

It has been proven that LGD-4033 improves bone health by boosting the minerals and consequently it leads to increased strength and bone density invariably. Naturally, osteoporosis is a condition where there are diminished bone minerals leading to frailty in bones. Additionally, a decline in bone mass could also be as a result of hormonal imbalance. Ligandrol acts like a hormone in the bones and muscles, therefore, raising the bone mass to prevent potential muscle injuries or fractures.

A clinical study has been carried out efficiently in rodents such as rats but not any human.

Below are the advantages of utilizing Ligandrol.



Selective Action

The benefits of using this drug would not just increase muscle mass but also help in anabolism. LGD-4033 acts quite selectively and it doesn’t alter other organs make up such as the liver. Actually, liver function tests(LFT) are intact and most importantly it also doesn’t target the kidney either. The blood pressure is also normal since most of its action is discerning.

In a clinical study, the patients who consumed 3mg of Ligandrol in eight months have added weight of 3ibs in eight months not just the inclusion of weight but also an increase in strength and response.

Safe to use

According to the doctors’ advice, LGD-4033 includes two different dosing phrases i.e. the loading and maintenance. Ligandrol increases blood flow to target organs such as kidney, heart and liver etc. That would relatively reduce blood pressure.


These effects are large as a consequence of wrong dosage plans or excessive usage (drug abuse), it might also be an indication that Ligandrol isn’t good for you. If you discover any of these consequences kindly see a physician.

  • Pain from the testis
  • Zero or no increase in joints after 5 to 6 weeks
  • Joint pains similar to arthritis
  • Gastrointestinal disturbances
  • Strength reduction
  • Insomnia
  • Erectile dysfunction
  • Distorted vision
  • High-pressure headache
  • Irregular menstrual cycle
  • Hair loss or alopecia
  • Skin discoloration


These reviews are based on different clinical research or study carried out on patients. Additionally, it has proven the potency of the medication.

  • No water retention in kidneys
  • Muscle advantage
  • Improved liver function test
  • Healthy neurology
  • Healthy physiology
  • Fat reduction
  • Better joint flexibility
  • Hormonal balance
  • No amenorrhea
  • Good cardiac rhythm
  • Tightness of loosed muscles

LGD-4033 has turned out to be quite efficient particularly in muscle wasting diseases or dystrophy. Having a selective function it also helps the body regain loosed weight by breaking unnecessary fats through lipolysis. Ligandrol also called Anabolicum as the name implies assists in anabolism and efficient protein synthesis. As strength, agility and stamina are raised concurrently this can be as a result of an increase in muscle and bone mass.

LGD-4033 (Ligandrol / Anabolicum)